Home based, tailored intervention to reduce rate of falls after stroke (FAST): randomised trial.
Clemson L, Scrivener K, Lannin N, Ada L, Day S, Lin I, Isbel S, Cusick A, Gardner B, Preston E, Heller G, Dean CM, FAST Study Group
Paper source
Home based, tailored intervention to reduce rate of falls after stroke (FAST): randomised trial.
This rigor review was examined and confirmed by Adcurare Editorial · July 6, 2026
How this rating was calculated▸
- ReportingKey resources partially met−0.25★
- Key resources under-identified (antibodies, cell lines, RRIDs)
This Adcurare Rigor Review uses AI Rigor Reviewers trained on a curated corpus of high-fidelity and retracted papers, with expert supervision and curation. It can still make mistakes; verify each finding against the source before relying on it.
This manuscript reports a well-designed phase 3 RCT that is methodologically rigorous overall, with a clear rationale, appropriate randomisation and blinding, and a prospective registration. The main weaknesses are a missing explicit informed consent statement and a brief absence of regulatory compliance wording, plus minor gaps in verifying statistical assumptions and outlier handling — all easily fixed before submission.
The paper was evaluated on all eight rigor dimensions; key resources was scored as not applicable because the study is a behavioural/exercise intervention without biological/chemical resources or bespoke software. The three reviewers largely converged, with minor divergence on ethical approvals (one warn vs. two pass) and key resources (one N/A vs. two pass) — the synthesised judgment resolved these by strictly applying the checklist-level rules. The statistical analysis verifier recomputed 8 tests consistently; see its coverage note for limitations.
8 major claims checked against the paper's own evidence: all adequately supported.
Recomputed 8 tests: 8 consistent, 0 inconsistent, 8 via agent-written checks.
6 copyedit issues flagged: mostly clarity, consistency, other.
Checked 31 references: 30 verified — 1 not checked.
1 data/code link checked; 0 live.
Registered (1 ID: ANZCTR). Reporting guideline cited: CONSORT.
The manuscript is ready to submit after minor edits. The only realistic barrier to acceptance is the missing explicit informed consent statement; once added, the paper meets or exceeds reporting standards for a clinical trial. No substantive validity concerns were identified.
- 1.HIGHethicsAdd a sentence to the Methods (Participants or Ethics statements) explicitly stating that written informed consent was obtained from all participants, e.g. 'All participants provided written informed consent prior to enrolment.'Informed consent is a standard ethical and editorial requirement; the current text only mentions capacity to consent as an inclusion criterion, not its actual acquisition.
- 2.HIGHethicsAdd a sentence to the Ethics statements section confirming the trial was conducted in accordance with the Declaration of Helsinki (or another recognised ethical framework).Regulatory compliance is expected by most journals; the paper currently implies it via CONSORT and trial registration, but does not explicitly state it.
- 3.HIGHstatisticsIn the Statistical analysis section, add a sentence verifying the assumptions of the negative binomial model (e.g. overdispersion) and ANOVA (e.g. normality, homogeneity of variance), or state that the sample size made these tests robust to minor violations.Assumption verification improves transparency and reproducibility; all three reviewers noted this as a minor gap.
- 4.HIGHreportingIn the Statistical analysis section, specify the type of ANOVA used (e.g. repeated measures, mixed), as noted by the copyedit pass.Clarifying the ANOVA type improves methodological replicability.
- 5.MEDIUMstatisticsAdd a statement to the Statistical analysis section describing the handling of outliers in the primary and secondary outcomes, even if no outliers were excluded.Outlier handling is a standard reporting element; its absence was flagged by two reviewers and the copyedit pass.
- 6.MEDIUMreportingConsider adding a patient and public involvement (PPI) statement to the Methods, as the authors note its absence as a limitation in the Discussion.Adding a PPI statement would address the limitation the authors themselves identified and strengthen the manuscript for submission.
- 7.MEDIUMreportingProvide the full TIDieR checklist as a supplementary file to enhance replicability of the intervention.A TIDieR checklist is best practice for complex intervention trials and was suggested by one reviewer.
- 8.MEDIUMdata codeIn the Data availability statement, clarify the access conditions (e.g. whether the data are openly available without restriction or require a request).Fully specifying access conditions meets tier-1 adequacy criteria for managed-access repositories.
- 9.LOWcopyeditFix the duplicated committee name in the Ethics statements: 'Macquarie University Human Research Ethics Committee Human Research Ethics Committee' should be a single instance.This typographical duplication was flagged by the copyedit pass and is a quick fix.
- 10.LOWcopyeditFix the extra semicolon and parentheses in Table 3, Step Test row: change '0.40 (0.29); (n=185)' to '0.40 (0.29); n=185' for consistency.Minor formatting inconsistency noted by the copyedit pass.
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